Toh H, Au Yeung WK, Unoki M, Matsumoto Y, Miki Y, Matsumura Y, Baba Y, Sado T, Nakamura Y, Matsuda M, Sasaki H. A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats. Curr Biol. 2025 May 15;35(12):2816.
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Toh H, Au Yeung WK, Unoki M, Matsumoto Y, Miki Y, Matsumura Y, Baba Y, Sado T, Nakamura Y, Matsuda M, Sasaki H. A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats. Curr Biol. 2025 May 15;35(12):2816.
PubMedリンク
Toriyama K, Au Yeung WK, Inoue A, Kurimoto K, Yabuta Y, Saitou M, Nakamura T, Nakano T, Sasaki H. DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells. BMC Genomics. 2024 Apr 5;25(1):344.
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Toriyama K, Au Yeung WK, Inoue A, Kurimoto K, Yabuta Y, Saitou M, Nakamura T, Nakano T, Sasaki H. DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells. BMC Genomics. 2024 Apr 5;25(1):344.
PubMedリンク
Uehara R, Au Yeung WK, Toriyama K, Ohishi H, Kubo N, Toh H, Suetake I, Shirane K, Sasaki H. The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes. PLoS Genet. 2023 Aug 1;19(8):e1010855.
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Uehara R, Au Yeung WK, Toriyama K, Ohishi H, Kubo N, Toh H, Suetake I, Shirane K, Sasaki H. The DNMT3A ADD domain is required for efficient de novo DNA methylation and maternal imprinting in mouse oocytes. PLoS Genet. 2023 Aug 1;19(8):e1010855.
PubMedリンク
Unoki M, Velasco G, Kori S, Arita K, Daigaku Y, Au Yeung WK, Fujimoto A, Ohashi H, Kubota T, Miyake K, Sasaki H. Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation. Hum Mol Genet. 2023 Apr 20;32(9):1439-1456.
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Unoki M, Velasco G, Kori S, Arita K, Daigaku Y, Au Yeung WK, Fujimoto A, Ohashi H, Kubota T, Miyake K, Sasaki H. Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation. Hum Mol Genet. 2023 Apr 20;32(9):1439-1456.
PubMedリンク
Maruyama O, Li Y, Narita H, Toh H, Au Yeung WK, Sasaki H. CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers. BMC Bioinformatics. 2022 Sep 12;23(1):371.
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Maruyama O, Li Y, Narita H, Toh H, Au Yeung WK, Sasaki H. CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers. BMC Bioinformatics. 2022 Sep 12;23(1):371.
PubMedリンク
Hasuwa H, Iwasaki YW, Au Yeung WK, Ishino K, Masuda H, Sasaki H, Siomi H. Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters. Nat Cell Biol. 2021 Sep;23(9):1002-1012.
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Hasuwa H, Iwasaki YW, Au Yeung WK, Ishino K, Masuda H, Sasaki H, Siomi H. Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters. Nat Cell Biol. 2021 Sep;23(9):1002-1012.
PubMedリンク
Au Yeung WK, Maruyama O, Sasaki H. A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns. BMC Bioinformatics. 2021 Jun 23;22(1):341.
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Au Yeung WK, Maruyama O, Sasaki H. A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns. BMC Bioinformatics. 2021 Jun 23;22(1):341.
PubMedリンク
Ishiuchi T, Abe S, Inoue K, Au Yeung WK, Miki Y, Ogura A, Sasaki H. Reprogramming of the histone H3.3 landscape in the early mouse embryo. Nat Struct Mol Biol. 2021 Jan;28(1):38-49.
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Ishiuchi T, Abe S, Inoue K, Au Yeung WK, Miki Y, Ogura A, Sasaki H. Reprogramming of the histone H3.3 landscape in the early mouse embryo. Nat Struct Mol Biol. 2021 Jan;28(1):38-49.
PubMedリンク
Cheung MY, Au Yeung WK,, Li KP, Lam HM. A Rice Immunophilin Homolog, OsFKBP12, Is a Negative Regulator of Both Biotic and Abiotic Stress Responses. Int J Mol Sci. 2020 Nov 20;21(22):8791.
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Cheung MY, Au Yeung WK,, Li KP, Lam HM. A Rice Immunophilin Homolog, OsFKBP12, Is a Negative Regulator of Both Biotic and Abiotic Stress Responses. Int J Mol Sci. 2020 Nov 20;21(22):8791.
PubMedリンク
Richard Albert J, Au Yeung WK, Toriyama K, Kobayashi H, Hirasawa R, Brind'Amour J, Bogutz A, Sasaki H, Lorincz M. Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo. Nat Commun. 2020 Oct 27;11(1):5417.
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Richard Albert J, Au Yeung WK, Toriyama K, Kobayashi H, Hirasawa R, Brind'Amour J, Bogutz A, Sasaki H, Lorincz M. Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo. Nat Commun. 2020 Oct 27;11(1):5417.
PubMedリンク
Du Z, Zheng H, Kawamura YK, Zhang K, Gassler J, Powell S, Xu Q, Lin Z, Xu K, Zhou Q, Ozonov EA, Véron N, Huang B, Li L, Yu G, Liu L, Au Yeung WK, Wang P, Chang L, Wang Q, He A, Sun Y, Na J, Sun Q, Sasaki H, Tachibana K, Peters AHFM, Xie W. Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos. Mol Cell. 2020 Feb 20;77(4):825-839.e7.
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Du Z, Zheng H, Kawamura YK, Zhang K, Gassler J, Powell S, Xu Q, Lin Z, Xu K, Zhou Q, Ozonov EA, Véron N, Huang B, Li L, Yu G, Liu L, Au Yeung WK, Wang P, Chang L, Wang Q, He A, Sun Y, Na J, Sun Q, Sasaki H, Tachibana K, Peters AHFM, Xie W. Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos. Mol Cell. 2020 Feb 20;77(4):825-839.e7.
PubMedリンク
Ohishi H, Au Yeung WK, Unoki M, Ichiyanagi K, Fukuda K, Maenohara S, Shirane K, Chiba H, Sado T, Sasaki H. Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells. Genes Cells. 2020 Jan;25(1):54-64.
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Ohishi H, Au Yeung WK, Unoki M, Ichiyanagi K, Fukuda K, Maenohara S, Shirane K, Chiba H, Sado T, Sasaki H. Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells. Genes Cells. 2020 Jan;25(1):54-64.
PubMedリンク
Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. Cell Rep. 2019 Apr 2;27(1):282-293.e4.
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Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. Cell Rep. 2019 Apr 2;27(1):282-293.e4.
PubMedリンク
Review Articles & Books
総説・著書
Au Yeung WK, Sasaki H. Low Input Genome-Wide DNA Methylation Analysis with Minimal Library Amplification. Methods Mol Biol. 2022;2509:233-250.
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Au Yeung WK, Sasaki H. Low Input Genome-Wide DNA Methylation Analysis with Minimal Library Amplification. Methods Mol Biol. 2022;2509:233-250.
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